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Targeted cardiac expression of soluble Fas prevents the development of heart failure in mice with cardiac-specific expression of MCP-1

Monocyte chemoattractant protein-1 (MCP-1) plays a crucial role in initiating coronary heart disease by recruiting monocytes/macrophages to the vessel wall. Transgenic mice with cardiac-specific expression of MCP-1 manifest cardiac inflammation and develop heart failure. The pathways mediating the d...

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Détails bibliographiques
Auteurs principaux: Niu, Jianli, Azfer, Asim, Deucher, Michael F., Goldschmidt-Clermont, Pascal J., Kolattukudy, Pappachan E.
Format: Artigo
Langue:Inglês
Publié: 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1523423/
https://ncbi.nlm.nih.gov/pubmed/16678847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2006.03.010
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