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Multivariable risk prediction can greatly enhance the statistical power of clinical trial subgroup analysis

BACKGROUND: When subgroup analyses of a positive clinical trial are unrevealing, such findings are commonly used to argue that the treatment's benefits apply to the entire study population; however, such analyses are often limited by poor statistical power. Multivariable risk-stratified analysi...

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Main Authors: Hayward, Rodney A, Kent, David M, Vijan, Sandeep, Hofer, Timothy P
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1523355/
https://ncbi.nlm.nih.gov/pubmed/16613605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2288-6-18
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