CDH1 promoter hypermethylation and E-cadherin protein expression in infiltrating breast cancer

BACKGROUND: The E-cadherin gene (CDH1) maps, at chromosome 16q22.1, a region often associated with loss of heterozygosity (LOH) in human breast cancer. LOH at this site is thought to lead to loss of function of this tumor suppressor gene and was correlated with decreased disease-free survival, poor...

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Autores principales: Caldeira, José Roberto F, Prando, Érika C, Quevedo, Francisco C, Neto, Francisco A Moraes, Rainho, Cláudia A, Rogatto, Silvia R
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2006
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1523210/
https://ncbi.nlm.nih.gov/pubmed/16512896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-6-48
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