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Control of neurotransmitter release by an internal gel matrix in synaptic vesicles
Neurotransmitters are stored in synaptic vesicles, where they have been assumed to be in free solution. Here we report that in Torpedo synaptic vesicles, only 5% of the total acetylcholine (ACh) or ATP content is free, and that the rest is adsorbed to an intravesicular proteoglycan matrix. This matr...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The National Academy of Sciences
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC152319/ https://ncbi.nlm.nih.gov/pubmed/12629223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0336914100 |
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