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UBF activates RNA polymerase I transcription by stimulating promoter escape
Ribosomal RNA gene transcription by RNA polymerase I (Pol I) is the driving force behind ribosome biogenesis, vital to cell growth and proliferation. The key activator of Pol I transcription, UBF, has been proposed to act by facilitating recruitment of Pol I and essential basal factor SL1 to rDNA pr...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1523182/ https://ncbi.nlm.nih.gov/pubmed/16858408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601221 |
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