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Human specific loss of olfactory receptor genes

Olfactory receptor (OR) genes constitute the basis for the sense of smell and are encoded by the largest mammalian gene superfamily of >1,000 genes. In humans, >60% of these are pseudogenes. In contrast, the mouse OR repertoire, although of roughly equal size, contains only ≈20% pseudogenes. We aske...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Gilad, Yoav, Man, Orna, Pääbo, Svante, Lancet, Doron
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2003
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152291/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12612342/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0535697100
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