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The matrix attachment region in the Chinese hamster dihydrofolate reductase origin of replication may be required for local chromatid separation

Centered in the Chinese hamster dihydrofolate reductase origin of replication is a prominent nuclear matrix attachment region (MAR). Indirect lines of evidence suggested that this MAR might be required for origin activation in early S phase. To test this possibility, we have deleted the MAR from a C...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Mesner, L. D., Hamlin, J. L., Dijkwel, P. A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2003
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152283/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12629222/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0437791100
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