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The matrix attachment region in the Chinese hamster dihydrofolate reductase origin of replication may be required for local chromatid separation

Centered in the Chinese hamster dihydrofolate reductase origin of replication is a prominent nuclear matrix attachment region (MAR). Indirect lines of evidence suggested that this MAR might be required for origin activation in early S phase. To test this possibility, we have deleted the MAR from a C...

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Main Authors: Mesner, L. D., Hamlin, J. L., Dijkwel, P. A.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC152283/
https://ncbi.nlm.nih.gov/pubmed/12629222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0437791100
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