Identification of a Functional Polymorphism of the Human Type 5 17β-Hydroxysteroid Dehydrogenase Gene Associated with Polycystic Ovary Syndrome.

CONTEXT: Polycystic ovary syndrome (PCOS) is characterized by chronic hyperandrogenic anovulation and is associated with insulin resistance. Its pathogenesis is believed to be multifactorial, and abnormal gene regulation could be one contributing factor. Type 5 17 beta-hydroxysteroid dehydrogenase (...

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Hauptverfasser: Qin, Kenan, Ehrmann, David A, Cox, Nancy, Refetoff4, Samuel, Rosenfield, Robert L
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1522092/
https://ncbi.nlm.nih.gov/pubmed/16263811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2005-2012
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