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Budding yeast Hed1 down-regulates the mitotic recombination machinery when meiotic recombination is impaired

In budding yeast, there are two RecA homologs: Rad51 and Dmc1. While Rad51 is involved in both mitotic and meiotic recombination, Dmc1 participates specifically in meiotic recombination. Here, we describe a meiosis-specific protein (Hed1) with a novel Rad51 regulatory function. Several observations...

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Bibliographic Details
Main Authors: Tsubouchi, Hideo, Roeder, G. Shirleen
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1522073/
https://ncbi.nlm.nih.gov/pubmed/16818607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1422506
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