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The Processing of eIF4GI by Human Rhinovirus Type 2 2A(pro): Relationship to Self-Cleavage and Role of Zinc

The 2A proteinase (2A(pro)) of human rhinoviruses (HRVs) is a cysteine protease containing a structurally important zinc ion. In the viral polyprotein, the enzyme cleaves between the C terminus of VP1 and its own N terminus. 2A(pro) also processes the two isoforms of the cellular protein, eukaryotic...

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Detalhes bibliográficos
Main Authors: Glaser, Walter, Triendl, Andrea, Skern, Tim
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC152162/
https://ncbi.nlm.nih.gov/pubmed/12663811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.8.5021-5025.2003
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