Human Papillomavirus Type 16 L1 Capsomeres Induce L1-Specific Cytotoxic T Lymphocytes and Tumor Regression in C57BL/6 Mice

We analyzed capsomeres of human papillomavirus type 16 (HPV16) consisting of the L1 major structural protein for their ability to trigger a cytotoxic T-cell (CTL) response. To this end, we immunized C57BL/6 mice and used the L1(165-173) peptide for ex vivo restimulation of splenocytes prior to analy...

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Hauptverfasser: Öhlschläger, Peter, Osen, Wolfram, Dell, Kerstin, Faath, Stefan, Garcea, Robert L., Jochmus, Ingrid, Müller, Martin, Pawlita, Michael, Schäfer, Klaus, Sehr, Peter, Staib, Caroline, Sutter, Gerd, Gissmann, Lutz
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC152157/
https://ncbi.nlm.nih.gov/pubmed/12663770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.8.4635-4645.2003
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