Template Dimerization Promotes an Acceptor Invasion-Induced Transfer Mechanism during Human Immunodeficiency Virus Type 1 Minus-Strand Synthesis

The biochemical mechanism of template switching by human immunodeficiency virus type 1 (HIV-1) reverse transcriptase and the role of template dimerization were examined. Homologous donor-acceptor template pairs derived from the HIV-1 untranslated leader region and containing the wild-type and mutant...

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Detalles Bibliográficos
Main Authors: Balakrishnan, Mini, Roques, Bernard P., Fay, Philip J., Bambara, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Recombination and Evolution
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC152154/
https://ncbi.nlm.nih.gov/pubmed/12663778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.8.4710-4721.2003
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