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Changes in Rhinovirus Protein 2C Allow Efficient Replication in Mouse Cells

Rhinovirus type 16 was found to replicate in mouse L cells that express the viral receptor, human intercellular adhesion molecule 1 (ICAM-1). However, infection of these cells at a low multiplicity of infection leads to no discernible cytopathic effect, and low virus titers are produced. A variant v...

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Autori principali: Harris, Julie R., Racaniello, Vincent R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC152148/
https://ncbi.nlm.nih.gov/pubmed/12663784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.8.4773-4780.2003
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