Human Herpesvirus 6 Variant A Glycoprotein H-Glycoprotein L-Glycoprotein Q Complex Associates with Human CD46

Human CD46 is a cellular receptor for human herpesvirus 6 (HHV-6). Virus entry into host cells requires a glycoprotein H (gH)-glycoprotein L (gL) complex. We show that the CD46 ectodomain blocked HHV-6 infection and bound a complex of gH-gL and the 80-kDa U100 gene product, designated glycoprotein Q...

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Main Authors: Mori, Yasuko, Yang, Xuwei, Akkapaiboon, Pilailuk, Okuno, Toshiomi, Yamanishi, Koichi
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC152135/
https://ncbi.nlm.nih.gov/pubmed/12663806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.8.4992-4999.2003
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