A Moloney Murine Leukemia Virus-Based Retrovirus with 4070A Long Terminal Repeat Sequences Induces a High Incidence of Myeloid as Well as Lymphoid Neoplasms

Retroviruses can be used to accelerate hematopoietic cancers predisposed to neoplastic disease by prior genetic manipulations such as in transgenic or knockout mice. The virus imparts a second neoplastic “hit,” providing evidence that the initial hit is transforming. In the present study, a unique r...

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Bibliografiske detaljer
Main Authors: Wolff, Linda, Koller, Richard, Hu, Xinrong, Anver, Miriam R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC152129/
https://ncbi.nlm.nih.gov/pubmed/12663802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.8.4965-4971.2003
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