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Human Immunodeficiency Virus Type 1 Assembly and Lipid Rafts: Pr55(gag) Associates with Membrane Domains That Are Largely Resistant to Brij98 but Sensitive to Triton X-100

The assembly and budding of human immunodeficiency virus type 1 (HIV-1) at the plasma membrane are directed by the viral core protein Pr55(gag). We have analyzed whether Pr55(gag) has intrinsic affinity for sphingolipid- and cholesterol-enriched raft microdomains at the plasma membrane. Pr55(gag) ha...

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Detalhes bibliográficos
Main Authors: Holm, Kirsi, Weclewicz, Katarzyna, Hewson, Roger, Suomalainen, Maarit
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC152122/
https://ncbi.nlm.nih.gov/pubmed/12663787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.8.4805-4817.2003
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