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Noninvasive methods for measuring DNA alkylation in experimental animals and humans.

Alkylpurines are liberated from alkylated DNA by glycosylase repair enzymes and, in most cases, excreted in urine without further metabolism. This phenomenon forms the basis of noninvasive methods to measure DNA alkylation in vivo. In the case of methyl adducts, such as 7-methylguanine (7-MeGua), na...

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Bibliografski detalji
Glavni autori: Shuker, D E, Prevost, V, Friesen, M D, Bartsch, H
Format: Artigo
Jezik:Inglês
Izdano: 1993
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1521165/
https://ncbi.nlm.nih.gov/pubmed/8143609
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