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Poliovirus CRE-Dependent VPg Uridylylation Is Required for Positive-Strand RNA Synthesis but Not for Negative-Strand RNA Synthesis

The cis-acting replication element (CRE) is a 61-nucleotide stem-loop RNA structure found within the coding sequence of poliovirus protein 2C. Although the CRE is required for viral RNA replication, its precise role(s) in negative- and positive-strand RNA synthesis has not been defined. Adenosine in...

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Main Authors: Murray, Kenneth E., Barton, David J.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC152113/
https://ncbi.nlm.nih.gov/pubmed/12663781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.8.4739-4750.2003
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