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Neisseria meningitidis RTX Proteins Are Not Required for Virulence in Infant Rats

RTX cytotoxins play an important role in virulence of numerous gram-negative pathogens. Unexpectedly, however, we show here that the RTX proteins of Neisseria meningitidis are dispensable for virulence in the infant rat model of infection.

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Détails bibliographiques
Publié dans:Infect Immun
Auteurs principaux: Forman, Stanislav, Linhartova, Irena, Osicka, Radim, Nassif, Xavier, Sebo, Peter, Pelicic, Vladimir
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152105/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12654851/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.4.2253-2257.2003
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