Helicobacter pylori Mutants Defective in RuvC Holliday Junction Resolvase Display Reduced Macrophage Survival and Spontaneous Clearance from the Murine Gastric Mucosa

Homologous recombination contributes to the extraordinary genetic diversity of Helicobacter pylori and may be critical for surface antigen expression and adaptation to environmental challenges within the stomach. We generated isogenic, nonpolar H. pylori ruvC mutants to investigate the function of R...

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Vydáno v:	Infect Immun
Hlavní autoři:	Loughlin, Michael F., Barnard, Faye M., Jenkins, David, Sharples, Gary J., Jenks, Peter J.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2003
Témata:	Molecular Pathogenesis
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152077/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12654822/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.4.2022-2031.2003
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