A New Vaccine against Tuberculosis Affords Greater Survival after Challenge than the Current Vaccine in the Guinea Pig Model of Pulmonary Tuberculosis

Tuberculosis (TB) remains an enormous global health problem, and a new vaccine against TB more potent than the current inadequate vaccine, Mycobacterium bovis BCG, is urgently needed. We describe a recombinant BCG vaccine (rBCG30) expressing and secreting the 30-kDa major secretory protein of Mycoba...

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Detalles Bibliográficos

Publicado en:	Infect Immun
Principais autores:	Horwitz, Marcus A., Harth, Günter
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2003
Assuntos:	Microbial Immunity and Vaccines
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152073/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12654780/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.4.1672-1679.2003
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