Genetic Organization and Iron-Responsive Regulation of the Brucella abortus 2,3-Dihydroxybenzoic Acid Biosynthesis Operon, a Cluster of Genes Required for Wild-Type Virulence in Pregnant Cattle

Brucella abortus reportedly produces the monocatechol siderophore 2,3-dihydroxybenzoic acid (2,3-DHBA) in response to iron limitation. Nucleotide sequence analysis of the cloned DHBA biosynthesis locus from virulent B. abortus 2308 and genetic complementation of defined Escherichia coli mutants were...

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Bibliographic Details
Main Authors: Bellaire, Bryan H., Elzer, Philip H., Hagius, Sue, Walker, Joel, Baldwin, Cynthia L., Roop II, R. Martin
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Molecular Pathogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC152065/
https://ncbi.nlm.nih.gov/pubmed/12654793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.4.1794-1803.2003
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