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Permissive role of thrombopoietin and granulocyte colony-stimulating factor receptors in hematopoietic cell fate decisions in vivo

The question of whether extracellular signals influence hematopoiesis by instructing stem cells to commit to a specific hematopoietic lineage (instructive model) or solely by permitting the survival and proliferation of predetermined progenitors (permissive model) has been controversial since the di...

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Detalhes bibliográficos
Main Authors: Stoffel, Ruedi, Ziegler, Sandra, Ghilardi, Nico, Ledermann, Birgit, de Sauvage, Frederic J., Skoda, Radek C.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC15199/
https://ncbi.nlm.nih.gov/pubmed/9892696
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