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Synthesis and biological evaluation of antagonists of growth hormone-releasing hormone with high and protracted in vivo activities

Some antagonists of human growth hormone-releasing hormone (hGH-RH) synthesized previously were shown to inhibit in vivo proliferation of various human cancers in nude mice. However, the activity of these analogs requires an increase to assure clinical efficacy. In an attempt to prepare hGH-RH antag...

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Main Authors: Varga, József L., Schally, Andrew V., Csernus, Valér J., Zarándi, Márta, Halmos, Gábor, Groot, Kate, Rékási, Zoltán
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC15198/
https://ncbi.nlm.nih.gov/pubmed/9892695
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