Elucidation of catalytic specificities of human cytochrome P450 and glutathione S-transferase enzymes and relevance to molecular epidemiology.

A number of different approaches have been used to determine the catalytic selectivity of individual human enzymes toward procarcinogens. Studies with cytochrome P450 (P450) enzymes and glutathione S-transferases are summarized here, and recent work with pyrrolizidine alkaloids, aflatoxins, 4,4'...

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Bibliographic Details
Main Authors: Guengerich, F P, Shimada, T, Raney, K D, Yun, C H, Meyer, D J, Ketterer, B, Harris, T M, Groopman, J D, Kadlubar, F F
Format: Artigo
Language:Inglês
Published: 1992
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1519604/
https://ncbi.nlm.nih.gov/pubmed/1486866
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