Expression, Purification, and Characterization of AknX Anthrone Oxygenase, Which Is Involved in Aklavinone Biosynthesis in Streptomyces galilaeus

In streptomycete anthracycline biosynthetic gene clusters, small open reading frames are located just upstream of minimal polyketide synthase genes. aknX is such a gene found in the aklavinone-aclacinomycin biosynthetic gene cluster of Streptomyces galilaeus. In order to identify its function, the a...

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Bibliographic Details
Main Authors: Chung, Jin-young, Fujii, Isao, Harada, Shigeharu, Sankawa, Ushio, Ebizuka, Yutaka
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Enzymes and Proteins
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC151955/
https://ncbi.nlm.nih.gov/pubmed/12399480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.22.6115-6122.2002
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