Inducible costimulator is essential for collagen-induced arthritis

CD4(+) helper Th cells play a major role in the pathogenesis of rheumatoid arthritis. Th cell activation, differentiation, and immune function are regulated by costimulatory molecules. Inducible costimulator (ICOS) is a novel costimulatory receptor expressed on activated T cells. We, as well as othe...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Nurieva, Roza I., Treuting, Piper, Duong, Julie, Flavell, Richard A., Dong, Chen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 2003
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151904/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12618524/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI17321
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