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Mechano-oxidative coupling by mitochondria induces proinflammatory responses in lung venular capillaries

Elevation of lung capillary pressure causes exocytosis of the leukocyte adhesion receptor P-selectin in endothelial cells (ECs), indicating that lung ECs generate a proinflammatory response to pressure-induced stress. To define underlying mechanisms, we followed the EC signaling sequence leading to...

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Detalhes bibliográficos
Main Authors: Ichimura, Hideo, Parthasarathi, Kaushik, Quadri, Sadiqa, Issekutz, Andrew C., Bhattacharya, Jahar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC151903/
https://ncbi.nlm.nih.gov/pubmed/12618523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317271
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