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Graft-versus-host disease can be separated from graft-versus-lymphoma effects by control of lymphocyte trafficking with FTY720

Graft-versus-host disease (GvHD) mediated by donor T cells recognizing host alloantigens is associated with beneficial graft-versus-tumor effects in recipients of allogeneic hematopoietic cell transplants. Since leukemias and lymphomas reside largely within the lymphohematopoietic system, we have pr...

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Publicat a:J Clin Invest
Autors principals: Kim, Yong-Mi, Sachs, Teviah, Asavaroengchai, Wannee, Bronson, Roderick, Sykes, Megan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151899/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12618520/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI16950
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