Osteopetrosis and thalamic hypomyelinosis with synaptic degeneration in DAP12-deficient mice

Deletions in the DAP12 gene in humans result in Nasu-Hakola disease, characterized by a combination of bone fractures and psychotic symptoms similar to schizophrenia, rapidly progressing to presenile dementia. However, it is not known why these disorders develop upon deficiency in DAP12, an immunore...

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Détails bibliographiques

Publié dans:	J Clin Invest
Auteurs principaux:	Kaifu, Tomonori, Nakahara, Jin, Inui, Masanori, Mishima, Kenichi, Momiyama, Toshihiko, Kaji, Mitsuji, Sugahara, Akiko, Koito, Hisami, Ujike-Asai, Azusa, Nakamura, Akira, Kanazawa, Kiyoshi, Tan-Takeuchi, Kyoko, Iwasaki, Katsunori, Yokoyama, Wayne M., Kudo, Akira, Fujiwara, Michihiro, Asou, Hiroaki, Takai, Toshiyuki
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 2003
Sujets:	Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151867/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12569157/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI16923
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