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The Relationship between Agonist Potency and AMPA Receptor Kinetics
AMPA-type glutamate receptors are tetrameric ion channels that mediate fast excitatory synaptic transmission in the mammalian brain. When agonists occupy the binding domain of individual receptor subunits, this domain closes, triggering rearrangements that couple agonist binding to channel opening....
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Biophysical Society
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1518651/ https://ncbi.nlm.nih.gov/pubmed/16731549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.084426 |
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