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The Relationship between Agonist Potency and AMPA Receptor Kinetics

AMPA-type glutamate receptors are tetrameric ion channels that mediate fast excitatory synaptic transmission in the mammalian brain. When agonists occupy the binding domain of individual receptor subunits, this domain closes, triggering rearrangements that couple agonist binding to channel opening....

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Autori principali: Zhang, Wei, Robert, Antoine, Vogensen, Stine B., Howe, James R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Biophysical Society 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1518651/
https://ncbi.nlm.nih.gov/pubmed/16731549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.084426
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