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A Computational Model Integrating Electrophysiology, Contraction, and Mitochondrial Bioenergetics in the Ventricular Myocyte

An intricate network of reactions is involved in matching energy supply with demand in the heart. This complexity arises because energy production both modulates and is modulated by the electrophysiological and contractile activity of the cardiac myocyte. Here, we present an integrated mathematical...

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Detalhes bibliográficos
Main Authors: Cortassa, Sonia, Aon, Miguel A., O'Rourke, Brian, Jacques, Robert, Tseng, Hsiang-Jer, Marbán, Eduardo, Winslow, Raimond L.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1518641/
https://ncbi.nlm.nih.gov/pubmed/16679365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.076174
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