Modulation of tumor growth by inhibitory Fcγ receptor expressed by human melanoma cells

The efficacy of anti-tumor IgG reflects the balance between opposing signals mediated by activating and inhibitory Fcγ receptors (FcγRs) expressed by effector cells. Here, we show that human malignant melanoma cells express the inhibitory low-affinity Fcγ receptor FcγRIIB1 in 40% of tested metastase...

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Main Authors: Cassard, Lydie, Cohen-Solal, Joël F.G., Galinha, Annie, Sastre-Garau, Xavier, Mathiot, Claire, Galon, Jérôme, Dorval, Thierry, Bernheim, Alain, Fridman, Wolf H., Sautès-Fridman, Catherine
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC151807/
https://ncbi.nlm.nih.gov/pubmed/12438452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI15454
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