Genetics of Mefloquine Resistance in the Rodent Malaria Parasite Plasmodium chabaudi

The genetic determinants of resistance to mefloquine in malaria parasites are unclear. Some studies have implied that amplification of, or mutations in, the multidrug resistance gene pfmdr1 in Plasmodium falciparum may be involved. Using the rodent malaria model Plasmodium chabaudi, we investigated...

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Detalhes bibliográficos
Main Authors: Cravo, Pedro V. L., Carlton, Jane M.-R., Hunt, Paul, Bisoni, Laura, Padua, Rose Ann, Walliker, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC151772/
https://ncbi.nlm.nih.gov/pubmed/12543682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.2.709-718.2003
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