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Efficacy of Amphotericin B or Itraconazole in a Murine Model of Central Nervous System Aspergillus Infection

Given the greater than 90% lethality of clinical central nervous system (CNS) aspergillosis despite current therapies, there is a need for an animal model to study therapeutic strategies. We previously established a model of CNS aspergillosis by intracerebral infection and report here the results of...

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Publicado no:Antimicrob Agents Chemother
Principais autores: Chiller, Tom M., Sobel, Raymond A., Capilla Luque, Javier, Clemons, Karl V., Stevens, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2003
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151760/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12543700/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.2.813-815.2003
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