Phenothiazines and Thioxanthenes Inhibit Multidrug Efflux Pump Activity in Staphylococcus aureus

Efflux-related multidrug resistance (MDR) is a significant means by which bacteria can evade the effects of selected antimicrobial agents. Genome sequencing data suggest that Staphylococcus aureus may possess numerous chromosomally encoded MDR efflux pumps, most of which have not been characterized....

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Bibliographic Details
Main Authors: Kaatz, Glenn W., Moudgal, Varsha V., Seo, Susan M., Kristiansen, Jette E.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC151737/
https://ncbi.nlm.nih.gov/pubmed/12543683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.2.719-726.2003
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