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The N-Terminal 24 Amino Acids of the p55 Gamma Regulatory Subunit of Phosphoinositide 3-Kinase Binds Rb and Induces Cell Cycle Arrest

Although phosphoinositide 3-kinase (PI 3-kinase) is essential for cell cycle progression, the molecular mechanisms that regulate its diverse biological effects are poorly understood. We demonstrate here that Rb, a key regulator of cell cycle progression, associates with p55 kDa (p55α and p55γ) regul...

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Detalhes bibliográficos
Main Authors: Xia, Xianmin, Cheng, Aiwu, Akinmade, Damilola, Hamburger, Anne W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC151709/
https://ncbi.nlm.nih.gov/pubmed/12588990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.5.1717-1725.2003
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