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The effects of intravenous pamidronate on the bone tissue of children and adolescents with osteogenesis imperfecta

Cyclical pamidronate infusions increase bone mass in children suffering from osteogenesis imperfecta. The histological basis for these effects remains unknown. Therefore, we compared parameters of iliac bone histomorphometry from 45 patients before and after 2.4 ± 0.6 years of pamidronate treatment...

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Autori principali: Rauch, Frank, Travers, Rose, Plotkin, Horacio, Glorieux, Francis H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC151613/
https://ncbi.nlm.nih.gov/pubmed/12417568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI15952
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