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Insights into the molecular mechanisms of bradycardia-triggered arrhythmias in long QT-3 syndrome

Congenital long QT syndrome is a rare disease in which the electrocardiogram QT interval is prolonged due to dysfunctional ventricular repolarization. Variant 3 (LQT-3) is associated with mutations in SCN5A, the gene coding for the heart Na(+) channel α subunit. Arrhythmias in LQT-3 mutation carrier...

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Detalles Bibliográficos
Main Authors: Clancy, Colleen E., Tateyama, Michihiro, Kass, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC151612/
https://ncbi.nlm.nih.gov/pubmed/12417563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI15928
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