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In vivo regulation of plasminogen function by plasma carboxypeptidase B

The major functions of plasminogen (Plg) in fibrinolysis and cell migration depend on its binding to carboxy-terminal lysyl residues. The ability of plasma carboxypeptidase B (pCPB) to remove these residues suggests that it may act as a suppressor of these Plg functions. To evaluate this role of pCP...

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Pubblicato in:J Clin Invest
Autori principali: Swaisgood, Carmen M., Schmitt, Detlef, Eaton, Dan, Plow, Edward F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2002
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151605/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12417566/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI15082
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