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Binding Dynamics of Structural Nucleoporins Govern Nuclear Pore Complex Permeability and May Mediate Channel Gating

The nuclear pore complex (NPC) is a permeable sieve that can dilate to facilitate the bidirectional translocation of a wide size range of receptor-cargo complexes. The binding of receptors to FG nucleoporin docking sites triggers channel gating by an unknown mechanism. Previously, we used deoxygluco...

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Publicado en:Mol Cell Biol
Autores principales: Shulga, Nataliya, Goldfarb, David S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2003
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151542/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12509452/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.2.534-542.2003
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