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Structural basis of two-stage voltage-dependent activation in K(+) channels

The structure of the voltage sensor and the detailed physical basis of voltage-dependent activation in ion channels have not been determined. We now have identified conserved molecular rearrangements underlying two major voltage-dependent conformational changes during activation of divergent K(+) ch...

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Autors principals: Silverman, William R., Roux, Benoît, Papazian, Diane M.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC151444/
https://ncbi.nlm.nih.gov/pubmed/12606713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0636603100
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