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Pathogen DNA as target for host-generated oxidative stress: Role for repair of bacterial DNA damage in Helicobacter pylori colonization

Helicobacter pylori elicits an oxidative stress during host colonization. This oxidative stress is known to cause lesions in the host DNA. Here we addressed the question as to whether the pathogen DNA is subject to lethal or mutational damage by the host-generated oxidative response. H. pylori Hpnth...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: O'Rourke, Eyleen J., Chevalier, Catherine, Pinto, A. Viviana, Thiberge, Jean Michel, Ielpi, Luis, Labigne, Agnès, Radicella, J. Pablo
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151419/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12601164/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0337641100
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