Quantitative proteomic analysis indicates increased synthesis of a quinolone by Pseudomonas aeruginosa isolates from cystic fibrosis airways

The opportunistic bacterial pathogen Pseudomonas aeruginosa colonizes airways of individuals with cystic fibrosis (CF) with resultant chronic destructive lung disease. P. aeruginosa adaptation to the CF airway includes biofilm formation and antibiotic resistance. Isolates from asymptomatic individua...

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Bibliographic Details
Main Authors: Guina, Tina, Purvine, Samuel O., Yi, Eugene C., Eng, Jimmy, Goodlett, David R., Aebersold, Ruedi, Miller, Samuel I.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2003
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC151416/
https://ncbi.nlm.nih.gov/pubmed/12601166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0435846100
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