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The purine salvage enzyme hypoxanthine guanine xanthine phosphoribosyl transferase is a major target antigen for cell-mediated immunity to malaria

Although there is good evidence that immunity to the blood stages of malaria parasites can be mediated by different effector components of the adaptive immune system, target antigens for a principal component, effector CD4(+) T cells, have never been defined. We generated CD4(+) T cell lines to frac...

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Detalhes bibliográficos
Main Authors: Makobongo, Morris O., Riding, George, Xu, Huji, Hirunpetcharat, Chakrit, Keough, Dianne, de Jersey, John, Willadsen, Peter, Good, Michael F.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC151391/
https://ncbi.nlm.nih.gov/pubmed/12594331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0337629100
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