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ROC and confusion analysis of structure comparison methods identify the main causes of divergence from manual protein classification

BACKGROUND: Current classification of protein folds are based, ultimately, on visual inspection of similarities. Previous attempts to use computerized structure comparison methods show only partial agreement with curated databases, but have failed to provide detailed statistical and structural analy...

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Detalhes bibliográficos
Main Authors: Sam, Vichetra, Tai, Chin-Hsien, Garnier, Jean, Gibrat, Jean-Francois, Lee, Byungkook, Munson, Peter J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1513609/
https://ncbi.nlm.nih.gov/pubmed/16613604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-7-206
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