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Hybridization interactions between probesets in short oligo microarrays lead to spurious correlations

BACKGROUND: Microarrays measure the binding of nucleotide sequences to a set of sequence specific probes. This information is combined with annotation specifying the relationship between probes and targets and used to make inferences about transcript- and, ultimately, gene expression. In some situat...

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Bibliografiske detaljer
Main Authors: Okoniewski, Michał J, Miller, Crispin J
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1513401/
https://ncbi.nlm.nih.gov/pubmed/16749918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-7-276
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