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The C-terminal domain phosphatase and transcription elongation activities of FCP1 are regulated by phosphorylation

The C-terminal domain (CTD) of the largest subunit of RNA polymerase II (RNAPII) is heavily phosphorylated during the transition from transcription initiation to the establishment of an elongation-competent transcription complex. FCP1 is the only phosphatase known to be specific for the CTD of the l...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Friedl, Erika M., Lane, William S., Erdjument-Bromage, Hediye, Tempst, Paul, Reinberg, Danny
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151340/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12591939/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2628049100
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