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MecA, an adaptor protein necessary for ClpC chaperone activity

ClpC of Bacillus subtilis is an ATP-dependent HSP100/Clp protein involved in general stress survival. A complex of ClpC with the protease ClpP and the adaptor protein MecA also controls competence development by regulated proteolysis of the transcription factor ComK. We investigated the in vitro cha...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Schlothauer, Tilman, Mogk, Axel, Dougan, David A., Bukau, Bernd, Turgay, Kürşad
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151336/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12598648/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0535717100
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