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Structure and Orientation of Pardaxin Determined by NMR Experiments in Model Membranes

Pardaxins are a class of ichthyotoxic peptides isolated from fish mucous glands. Pardaxins physically interact with cell membranes by forming pores or voltage-gated ion channels that disrupt cellular functions. Here we report the high-resolution structure of synthetic pardaxin Pa4 in sodium dodecylp...

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Detalhes bibliográficos
Main Authors: Porcelli, Fernando, Buck, Bethany, Lee, Dong-Kuk, Hallock, Kevin J., Ramamoorthy, Ayyalusamy, Veglia, Gianluigi
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1513189/
https://ncbi.nlm.nih.gov/pubmed/15292173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M405454200
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